Taking profits phobia- when do you cash out?

I've been in crypto since 2017, and while I've gotten to grips with a lot of things the space has to offer, taking profits has not been one of them.

I struggle to sell literally anything - even the mental battle to sell a shitcoin I knew was going nowhere has been monumental. I can't shut off the 'what if' voice inside my head - what if it goes to the moon?

With another bull run potentially looming, I really want to seriously consider some profit taking - especially on my alts - so I'm wondering how the community does it?

Are you a perpetual hodler like me? Or do you have a solid system in place as to when you cash out and if you do is it the same for all your coins?