What are some of the things you feel would be the death of Crypto, like full scale dead to the ground death?

Sorry to bring in some pessimism in this optimistic run of form we are having but I have this inate nature to become a little skeptical when something good happens so was wondering this question, what will be the signal for the death of Crypto and when will it happen if it does

I have some invested in various coins and definitely going to be accumulating more as time passes, but as the bag gets bigger (for example 100k plus) in the years you're going to start questioning wait what if I suddenly lose everything, what if this entire project fails, the 5 or so years of effort and time is gone to waste

I know the tendancy to become more paranoid as your investment grows. This is for those who have gone in 100% into this project and slowly started accumulating that it grows by a large amount in few years.

I don't know about everyone else but as much as I believe in something I reserve to being skeptical in nature.